The COA Vault

The intracellular fluid naturally runs 30× more potassium than sodium. Our extracellular fluid runs the opposite. Electrolyte drinks that pile on sodium without matching potassium widen that gap. MNRL 01 is formulated at a 3.3:1 K:Na ratio based on published research supporting potassium-forward electrolyte delivery.

BMJ 2013; 346:f1868

Vitamin B6 as pyridoxal-5-phosphate (P5P) — already active, no conversion needed — is included to support the body's use of magnesium. We co-deliver the two as the rationale for inclusion, drawing on published research on magnesium with active B6.

Uysal N, et al. J Am Coll Nutr 2017

Taurine is one of the body's primary organic osmolytes. It helps regulate cell volume during osmotic stress, supporting the gradient your minerals just established. Most hydration products ignore osmolytes entirely.

Amino Acids 2012; 43(5)

In a controlled study, roughly 3mg/day of boron was associated with reduced urinary excretion of magnesium and calcium in postmenopausal women on a low-boron diet. The evidence is population-specific, so we include boron as a supporting nutrient for mineral retention — not a headline benefit.

Nielsen FH, et al. FASEB J 1987;1(5):394-397

Sodium and glucose are absorbed together across the intestinal wall via the SGLT1 transporter, and water follows. This is the established mechanism behind oral rehydration therapy. Without a functional dose of glucose, sodium absorbs less efficiently and cellular hydration lags. MNRL 01 uses the functional minimum — enough to activate the cotransport pathway, not enough to act as a sweetener.

Wright EM et al. Physiol Rev. 2011;91(2):733-94